Calreticulin 3 Protein (CALR3) (AA 20-384)
Aperçu rapide pour Calreticulin 3 Protein (CALR3) (AA 20-384) (ABIN5853563)
Antigène
Voir toutes Calreticulin 3 (CALR3) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 20-384
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Séquence
- MTVYFQEEFL DGEHWRNRWL QSTNDSRFGH FRLSSGKFYG HKEKDKGLQT TQNGRFYAIS ARFKPFSNKG KTLVIQYTVK HEQKMDCGGG YIKVFPADID QKNLNGKSQY YIMFGPDICG FDIKKVHVIL HFKNKYHENK KLIRCKVDGF THLYTLILRP DLSYDVKIDG QSIESGSIEY DWNLTSLKKE TSPAESKDWE QTKDNKAQDW EKHFLDASTS KQSDWNGDLD GDWPAPMLQK PPYQDGLKPE GIHKDVWLHR KMKNTDYLTQ YDLSEFENIG AIGLELWQVR SGTIFDNFLI TDDEEYADNF GKATWGETKG PEREMDAIQA KEEMKKAREE EEEELLSGKI NRHEHYFNQF HRRNEL
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Purification
- > 90% by SDS-PAGE
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Denatured
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Calreticulin 3 (CALR3)
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Autre désignation
- Calreticulin-2
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Sujet
- Calreticulin 3, also known as CALR3, is a member of the calreticulin (CRT) family. It is calcium-binding chaperones that are localized to the endoplasmic reticulum or sarcoplasmic reticulum in eukaryotes. CALR3 assists in the calreticulin/calnexin cycle, where it is involved in protein-folding, oligomeric assembly and quality control in the ER. With specific expression in testis, CALR3 has been implicated as a cancer-testis antigen due to its frequent expression in various cancers. Recombinant human CALR3 protein was expressed in E. coli.
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Poids moléculaire
- 43 kDa (366aa)
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NCBI Accession
- NP_659483
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Pathways
- Activation of Innate immune Response
Antigène
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